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KMID : 0383819560030010141
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Tuberculosis and Respiratory Diseases
1956 Volume.3 No. 1 p.141 ~ p.147
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The results of Ambulatory Treatment by Chemotherapy for T. B. patients
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변해원(邊海元)/Hae Won Pyun
이관희(李灌熙)/한용수(韓庸洙)/Kwan Hi Lee/Eung Soo Han
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Abstract
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We have observed 54 T.B. patients. at as interval of every 3 months, who have been
given Chemotherapy for th last 12 months, for the purpose of finding out when the
Chemotherapy brings the maximum effects and when the most suitable time for surgery
is. If we could find them out, it would save time and money in the treatment of th
patients.
The Result of the Above Observation.
1. Radiologieally highest rate of the improvement comes at the 6th months from the
start of Chemotherapy, The improvement continues even after that of the first 6th
month. but the ratio is very low comparing with the group at 6th month. The
percentage of the improvement is 44.4% at the 12 month.
2. Cavity closure rate is the highest at the 6th month and at the 9th month, but after
the 9th month, the ratio does not rise at all in the results. The ratio at 9th month is
37.7% and that at 12th month is same as that at 9th month.
3. Sputum conversion rate to negative result on culture. The highest conversion rate
is also at the 6th month. After 6th month the percentage of conversion rises but the
ratio is very low, especially so after the 9th month. Total conversion ate is 67.7% about
80% of which is at the 6th month. The results of our observation clearly indicates that
surgery should be made principally between the 6th month and the 9th month, after the
beginning of chemotherapy.
4. R.B.G. Sedimentation rate. We obtain 74% improvement even at 3rd month and
percentage kept going higher and at the 12th month the rate went as high as 90%.
5. Comperative observation of different regimen of Chemotherapy. Regimen of S.M
plus INAH showed about the same results in all phases of study. However S.M. plus
INAH regime was somewhat better in Radiological improvement and R.B.C.
sedimentation rate than other regimes. S.M. plus PAS regime showed slightly betterr
results in closure of cavity and bacteriological combertion rate of sputum. All results
except R.B.G. Sedimentation rate show that the time when the highest improvement is
obtained is between the 6th and 9th month of their chemotherapy.
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